Anti- CAD Antibody | FNab01183

Anti- CAD Antibody | FNab01183 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

synonyms: N/A

Molecular weight (observed) : 243 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, IF, FC, IP

Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Research Area: Metabolism