710
Anti- CAD Antibody | FNab01183
- SKU:
- 710-FNab01183-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- CAD Antibody | FNab01183 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
synonyms: N/A
Molecular weight (observed) : 243 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IHC, IF, FC, IP
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Research Area: Metabolism