Anti- Caspase 2 Antibody | FNab01287

Anti- Caspase 2 Antibody | FNab01287 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen: caspase 2, apoptosis-related cysteine peptidase

synonyms: CASP 2, CASP2, Caspase 2, ICH 1L, ICH 1L/1S, ICH1, NEDD 2, NEDD2, Protease ICH 1

Molecular weight (observed) : 50 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, IF, IHC, WB, IP

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:50-1:200

Research Area: Metabolism