Anti- Caspase 2 Antibody | FNab098281

Anti- Caspase 2 Antibody | FNab098281 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 2B10

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: CASP2 (Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution (PMID:15865942) .This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.

Immunogen: Caspase 2

synonyms: CASP 2, CASP2, Caspase 2, Caspase2, ICH 1L, ICH 1L/1S, ICH1, NEDD 2, NEDD2, Protease ICH 1

Molecular weight (observed) : 18, 32, 50 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:1000-1:6000

Research Area: Neuroscience, Immunology, Signal Transduction