Anti-Caspase-7 Antibody | A1752

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

A1752 | Anti-Caspase-7 Antibody DataSheet

Antibody Target: Caspase-7

Target Alternative Name: Apoptotic protease Mch-3, CMH-1, ICE-LAP3, ICE-like apoptotic protease 3, LICE2, MCH3

Tag Line: Polyclonal antibody to detect Caspase-7 in human and mouse samples.

Category: Cancer

Host: Rabbit

Isotype: IgG

Species Reactivities: Mouse, Human

Immunogen Sequence: Recombinant protein of human CASP7

Accession #: P55210

Gene ID: 840

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.1 mg/ml

Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3

Purification: Affinity purification

Application: Immunohistochemistry (IHC), Western Blotting, ELISA

Positive Control:

Application And Usages: WB 1:200-1:1000, IHC 1:25-1:100

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: True

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False