Anti- CD150 Antibody (PE conjugated) | FNab09790

Anti- CD150 Antibody (PE conjugated) | FNab09790 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein G purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rat

Clonality: monoclonal

Clone ID: 3B6

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoieticstem cell studies.

Immunogen: signaling lymphocytic activation molecule family member 1

synonyms: CDw150, Slamf1, Slam, ESTM51, IPO-3, 4933415F16, AA177906

Molecular weight (observed) : 11kd

Reactivity Species: Mouse

Tested Application: ELISA, IHC, IP, WB

Recomended Dillution : 1：10-1：50

Research Area: N/A