710
Anti- CD39 Antibody | FNab01474
- SKU:
- 710-FNab01474-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- CD39 Antibody | FNab01474 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: ENTPD1 (Ectonucleoside triphosphate diphosphohydrolase 1) is also named as CD39, NTPDase 1, Ecto-ATPDase 1 and belongs to the GDA1/CD39 NTPase family. In the nervous system, it can hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.It is a noncovalent tetrameric protein and that detergent inhibition of enzymatic activity is caused by dissociation of ectoapyrase tetramers into monomers (PMID: 9733785) .And it is a 70-to 100-kDa protein that is heavily N-glycosylated (PMID:7930580) . It has 3 isoforms produced by alternative splicing. CD39 preferentially occurred as a dimer that could be dissociated into monomeric forms. (PMID: 12694193) . The soluble isoform of CD39 (38-478 amino acid) locates to the extracellular part and FNab01474 recognizes both the 3 isoforms and soluble form of CD39 (38-478aa) molecule.
Immunogen: ectonucleoside triphosphate diphosphohydrolase 1
synonyms: ATPDase, CD39, DKFZp686D194, DKFZp686I093, Ecto apyrase, Ecto ATP diphosphohydrolase 1, Ecto ATPase 1, Ecto ATPDase 1, ENTPD1, FLJ40921, FLJ40959, NTPDase 1
Molecular weight (observed) : 75-95 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IF, WB
Recomended Dillution : WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Research Area: Stem Cells, Immunology, Metabolism, Cancer