Anti- CD39 Antibody | FNab01474

Anti- CD39 Antibody | FNab01474 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: ENTPD1 (Ectonucleoside triphosphate diphosphohydrolase 1) is also named as CD39, NTPDase 1, Ecto-ATPDase 1 and belongs to the GDA1/CD39 NTPase family. In the nervous system, it can hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.It is a noncovalent tetrameric protein and that detergent inhibition of enzymatic activity is caused by dissociation of ectoapyrase tetramers into monomers (PMID: 9733785) .And it is a 70-to 100-kDa protein that is heavily N-glycosylated (PMID:7930580) . It has 3 isoforms produced by alternative splicing. CD39 preferentially occurred as a dimer that could be dissociated into monomeric forms. (PMID: 12694193) . The soluble isoform of CD39 (38-478 amino acid) locates to the extracellular part and FNab01474 recognizes both the 3 isoforms and soluble form of CD39 (38-478aa) molecule.

Immunogen: ectonucleoside triphosphate diphosphohydrolase 1

synonyms: ATPDase, CD39, DKFZp686D194, DKFZp686I093, Ecto apyrase, Ecto ATP diphosphohydrolase 1, Ecto ATPase 1, Ecto ATPDase 1, ENTPD1, FLJ40921, FLJ40959, NTPDase 1

Molecular weight (observed) : 75-95 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IF, WB

Recomended Dillution : WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Research Area: Stem Cells, Immunology, Metabolism, Cancer