Anti- CLEC4M Antibody | FNab01757

Anti- CLEC4M Antibody | FNab01757 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. (Microbial infection) Acts as an attachment receptor for ebola virus (PubMed:12050398, PubMed:12502850) . Acts as an attachment receptor for hepatitis C virus (PubMed:15371595, PubMed:16816373) . Acts as an attachment receptor for HIV-1 (PubMed:21277928, PubMed:12502850) . Acts as an attachment receptor for human coronavirus 229E (PubMed:17037540) . Acts as an attachment receptor for human cytomegalovirus/HHV-5 (PubMed:12433371) . Acts as an attachment receptor for influenzavirus (PubMed:21191006) . Acts as an attachment receptor for SARS coronavirus (PubMed:15479853) . Acts as an attachment receptor for west-nile virus (PubMed:16415006) . Acts as an attachment receptor for Japanese encephalitis virus (PubMed:24623090) . Acts as an attachment receptor for Marburg virus glycoprotein (PubMed:15479853) . Recognition of M.bovis by dendritic cells may occur partially via this molecule (PubMed:21203928) .

Immunogen: C-type lectin domain family 4, member M

synonyms: CD209L, CD209L1, CD299

Molecular weight (observed) : N/A

Reactivity Species: Human

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200

Research Area: Immunology, Cardiovascular, Signal Transduction