Anti- Connexin-43 Antibody | FNab01861

Anti- Connexin-43 Antibody | FNab01861 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity) . May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles (By similarity) .

Immunogen: gap junction protein, alpha 1, 43kDa

synonyms: Connexin-43, CX43, DFNB38, Gap junction alpha 1 protein, GJA1, GJAL, ODDD

Molecular weight (observed) : 47 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP

Recomended Dillution : WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:50-1:500

Research Area: Signal Transduction