Anti-CoV-2, MERS & SARS-CoV NP Mouse IgG1 Antibody | A2063

SARS-CoV-2, MERS-CoV and SARS-CoV belong to the family of Coronaviridae and are characterized by large positive-sense RNA genome, that is about 28 - 30 kb in length. One unique feature of SARS-CoV-2, SARS-CoV and MERS-CoV is that two-thirds of the viral genome is translated into two large polyproteins whereas the remaining viral genome is transcribed into sub-genomic RNAs. The two large polyproteins encode multiple non-structural proteins that play an important role in viral replication and transcription. SARS-CoV-2, SARS-CoV and MERS-CoV transcribe multiple sub-genomic RNAs that encode four structural proteins, namely, envelope (E), membrane (M), spike (S), and nucleocapsid (N). Some of the main functions of the nucleocapsid protein are 1) to package the genomic of the virus into long and helical ribonucleoprotein (RNP) complexes, 2) to dimerize and associate with genomic RNA of the virus, as well as interact with other structural proteins of the virus, both of which functions are essential for viral assembly, 3) associate with ER-Golgi complex during virus budding, 4) assist in genomic RNA synthesis, 5) assist RNA chaperone proteins in proper folding of nucleic acids, and 6) play an important role in viral pathogenesis.

A2063 | Anti-CoV-2, MERS & SARS-CoV NP Mouse IgG1 Antibody DataSheet

Antibody Target: SARS-CoV-2, MERS & SARS-CoV NP

Target Alternative Name:

Tag Line: Purified mouse monoclonal antibody to detect SARS-CoV-2, MERS and SARS Coronavirus Nucleoprotein. Has no crossreactivity with Coronavirus OC43, NL63 and 229E

Category: Primary antibody

Host: Mouse

Isotype: IgG1

Species Reactivities: Human

Immunogen Sequence: Recombinant Coronavirus Nucleoprotein peptide

Accession #:

Gene ID:

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In 10 mM PBS, pH 7.2, 0.1% sodium azide

Purification: Affinity purified using protein A

Application: Immunofluorescence (IF),ELISA

Positive Control:

Application And Usages: ELISA, IF

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: False

Immunocytochemistry Verified: False

Immunofluorescence Verified: True

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: True

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False