Anti- COX2 Antibody | FNab10407

Anti- COX2 Antibody | FNab10407 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: COX2 (Prostaglandin G/H synthase 2; PTGS2) mediates the formation of prostaglandins from arachidonate. Its subunit structure is homodimer. The fully N-glycosylated PTGS2 is 72–74 kDa and the aglycosylated is 66 kDa (PMID:19656660 ) . It also expresses a band of 39 kDa after unspecific cleavage (PMID:17509125 ) . The 50 kDa band of fragmented PTGS2 has also previously been detected in AD brains (PMID:14724276 ) .

Immunogen: prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

synonyms: COX 2, COX2, Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2

Molecular weight (observed) : 50 kDa, 80 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IHC

Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Research Area: Cancer, Cardiovascular, Metabolism