710
Anti- CSPG4, NG2 Antibody | FNab02025
- SKU:
- 710-FNab02025-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- CSPG4, NG2 Antibody | FNab02025 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CSPG4, also named as HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16 and NG2, is a proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. CSPG4 may inhibit neurite outgrowth and growth cone collapse during axon regeneration. It is cell surface receptor for collagen alpha 2 (VI) which may confer cells ability to migrate on that substrate. CSPG4 may regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. It modulates the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin.
Immunogen: chondroitin sulfate proteoglycan 4
synonyms: CSPG4, HMW MAA, MCSP, MCSPG, MEL CSPG, MSK16, NG2
Molecular weight (observed) : 240-250 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recomended Dillution : WB: 1:500-1:5000; IHC: 1:50-1:500
Research Area: Signal Transduction, Cardiovascular, Developmental biology, Neuroscience, Stem Cells