26
Anti-CXCR4 Polyclonal Antibody | A2335
- SKU:
- 26-A2335-GEN
- Availability:
- Usually shipped in 5 working days
Description
CXCR4 is a receptor for the chemokine CXCL12 (SDF-1) that mediates signal transduction through the increase of intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. CXCR4 plays a role in regulating cell migration and binds bacterial lipopolysaccharide (LPS) to mediate an inflammatory response by the innate immune system. Along with CD4, CXCR4 acts as a coreceptor for the human immunodeficiency virus (HIV-1) to allow HIV entry into host cells. CXCR4 is also overexpressed in breast cancer cells.
A2335 | Anti-CXCR4 Polyclonal Antibody DataSheet
Antibody Target: Human CXCR4
Target Alternative Name: C-X-C Motif Chemokine Receptor 4; LESTR; Fusin; SDF-1 Receptor; CD184
Tag Line: A cell surface receptor that facilitates HIV entry into host cells
Category: GM-CSF
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Rat Human
Immunogen Sequence: KLH-conjugated synthetic peptide derived from human CXCR4
Accession #: P61073
Gene ID: 7852
Appearance: Liquid
Form: Rabbit polyclonal
Concentration:
Formulation: In 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide
Purification: Affinity chromatography
Application: Immunohistochemistry (IHC) Western Blotting
Positive Control:
Application And Usages:
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: TRUE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: TRUE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |