710
Anti- CYP4F3 Antibody | FNab02173
- SKU:
- 710-FNab02173-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- CYP4F3 Antibody | FNab02173 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Isoform CYP4F3A: Catalyzes the omega-hydroxylation of leukotriene-B (4), a potent chemoattractant for polymorphonuclear leukocytes, it has low activity for arachidonic acid. Isoform CYP4F3B: Shows arachidonic acid omega-hydroxylase activity by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE) (PubMed:11461919, PubMed:16820285) . Has a 30-fold higher Km for leukotriene-B (4) compared with CYP4F3A (PubMed:11461919) . Also converts eicosapentaenoate (EPA) to 20-hydroxyeicosapentaenoate (20-OH-EPA) (PubMed:16820285) . Acts as a polyunsaturated omega-3 fatty acids hydroxylase: mediates conversion of docosahexaenoate (DHA) to 22-hydroxydocosahexaenoate (PubMed:16820285) .
Immunogen: cytochrome P450, family 4, subfamily F, polypeptide 3
synonyms: LTB4H
Molecular weight (observed) : 60 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:500-1:2000
Research Area: Metabolism