Anti- Cytokeratin 18 Antibody | FNab02206

Anti- Cytokeratin 18 Antibody | FNab02206 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 6E3

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.

Immunogen: keratin 18

synonyms: CK 18, CYK18, Cytokeratin 18, K18, keratin 18, KRT18

Molecular weight (observed) : 48 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IF, IHC, IP

Recomended Dillution : WB: 1:5000-1:30000; IHC: 1:500-1:1000; IF: 1:100-1:300

Research Area: Cancer, Immunology, Cardiovascular