Anti- DCX Antibody | FNab02280

Anti- DCX Antibody | FNab02280 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.

Immunogen: doublecortin

synonyms: DBCN, DC, DCX, doublecortin, Doublin, Lis X, Lissencephalin X, LISX, SCLH, XLIS

Molecular weight (observed) : 40 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IP

Recomended Dillution : WB: 1:500-1:2000; IF: 1:20-1:200

Research Area: Neuroscience, Stem Cells, Signal Transduction, Developmental biology