BW
Anti-EIF2S1 monoclonal Antibody | MB62233
- SKU:
- BW-MB62233
- Availability:
- Usually ships in 5 working days
Description
Anti-EIF2S1 monoclonal Antibody | MB62233 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Monkey, Mouse, Rat, Dog
Application: IHC, WB
Application Range: WB 1:1000~2000, IHC 1:50
Background: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161) . The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]) . [supplied by OMIM]
Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: eukaryotic translation initiation factor 2 subunit alpha
Molecular Weight: 35.9 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A
Immunogen: Full length human recombinant protein of human EIF2S1 (NP_004085) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A