Anti- Endostatin Antibody | FNab02762

Anti- Endostatin Antibody | FNab02762 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Endostatin is a naturally-occurring 20-kDa C-terminal fragment derived from COL18A1 (also named as KNO) . It is reported to serve as an anti-angiogenic agent, similar to angiostatin and thrombospondin. It potently inhibits endothelial cell proliferation and inhibits endothelial cell angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. Endostatin is a broad spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors such as basic fibroblast growth factor (bFGF/FGF-2) and vascular endothelial growth factor (VEGF) .

Immunogen: collagen, type XVIII, alpha 1

synonyms: Endostatin

Molecular weight (observed) : 19 kDa, 27 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IP, IHC

Recomended Dillution : WB: 1:200-1:1000; IHC: 1:20-1:200

Research Area: Cardiovascular, Developmental biology