Anti-ER-alpha Antibody | A2016

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

A2016 | Anti-ER-alpha Antibody DataSheet

Antibody Target: ER-alpha

Target Alternative Name: ESR; NR3A1; Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1

Tag Line: Affinity purified rabbit polyclonal antibody to detect Estrogen receptor-alpha expression in human, mouse, rat, bovine, chicken and porcine samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Bovine, Porcine, Rat, Chicken, Mouse, Human

Immunogen Sequence: KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human ER-alpha

Accession #: P03372

Gene ID: 2099

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting

Positive Control:

Application And Usages: WB 1:500 - 1:1000, IHC 1:100 - 1:200, IF 1:100 - 1:500

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: True

Immunofluorescence Verified: True

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False