Anti- ERBB3 Antibody | FNab02828

Anti- ERBB3 Antibody | FNab02828 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778) . May also be activated by CSPG5 (PubMed:15358134) .

Immunogen: v-erb-b2 erythroblastic leukemia viral oncogene homolog 3

synonyms: c erbB 3, c erbB3, ErbB 3, ERBB3, erbB3 S, HER3, LCCS2, MDA BF 1, p180 ErbB3, p45 sErbB3, p85 sErbB3

Molecular weight (observed) : N/A

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recomended Dillution : IHC: 1:50-1:500

Research Area: Signal Transduction, Metabolism, Cardiovascular, Cancer, Immunology