Anti-ERBB4 Antibody | A1862

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

A1862 | Anti-ERBB4 Antibody DataSheet

Antibody Target: EBBR4

Target Alternative Name: HER4, ALS19, p180erbB4, ERBB4, erb-b2 receptor tyrosine kinase 4

Tag Line: Affinity purified Rabbit polyclonal to ERBB4

Category: Primary antibody

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Rat, Human

Immunogen Sequence: A synthetic peptide corresponding to a sequence within amino acids 1150-1250 of human ERBB4 (NP_005226.1).

Accession #: Q15303

Gene ID: 2066

Appearance: Liquid

Form: Liquid

Concentration:

Formulation: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification: Affinity purification

Application: Western Blotting

Positive Control:

Application And Usages: WB 1:500 - 1:2000

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: False

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False