Anti- FADS1 Antibody | FNab02943

Anti- FADS1 Antibody | FNab02943 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Isoform 2 does not exhibit any catalytic activity toward 20:3n-6, but it may enhance FADS2 activity (By similarity) . Isoform 1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) . Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA) (20:5n-3), respectively.

Immunogen: fatty acid desaturase 1

synonyms: FADSD5

Molecular weight (observed) : 52 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IF

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200

Research Area: Cardiovascular, Metabolism, Signal Transduction