710
Anti- FANCI Antibody | FNab03009
- SKU:
- 710-FNab03009-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- FANCI Antibody | FNab03009 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) . Participates in S phase and G2 phase checkpoint activation upon DNA damage.
Immunogen: Fanconi anemia, complementation group I
synonyms: KIAA1794
Molecular weight (observed) : 150 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IF
Recomended Dillution : WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200
Research Area: Epigenetics, Metabolism