Anti- FBLIM1 Antibody | FNab03028

Anti- FBLIM1 Antibody | FNab03028 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.

Immunogen: filamin binding LIM protein 1

synonyms: FBLP1

Molecular weight (observed) : 45-48 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IF, IHC, WB, IP

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200

Research Area: Cancer, Signal Transduction