Anti- Fibromodulin Antibody | FNab03120

Anti- Fibromodulin Antibody | FNab03120 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.

Immunogen: fibromodulin

synonyms: fibromodulin, FM, FMOD, KSPG fibromodulin, SLRR2E

Molecular weight (observed) : 45kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Research Area: Neuroscience, Stem Cells, Cardiovascular, Signal Transduction