Anti- FXN Antibody | FNab03255

Anti- FXN Antibody | FNab03255 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14 or 18kDa.

Immunogen: frataxin

synonyms: CyaY, d FXN, FA, FARR, frataxin, Frataxin (81 210), Frataxin, mitochondrial, FRDA, Friedreich ataxia protein, FXN, i FXN Frataxin (56 210), m56 FXN Frataxin (78 210), m78 FXN Frataxin mature form, m81 FXN, X25

Molecular weight (observed) : 14 kDa

Reactivity Species: Human

Tested Application: ELISA

Recomended Dillution : WB: 1:500-1:2000

Research Area: Cancer, Neuroscience, Metabolism, Signal Transduction