710
Anti- GAD2 Antibody | FNab03291
- SKU:
- 710-FNab03291-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- GAD2 Antibody | FNab03291 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Immunogen: glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
synonyms: GAD65
Molecular weight (observed) : 70 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB, IP
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
Research Area: Neuroscience, Metabolism, Epigenetics