26
Anti-GDF-15 Antibody | A2038
- SKU:
- 26-A2038-100-GEN
- Availability:
- Usually shipped in 5 working days
Description
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress.
A2038 | Anti-GDF-15 Antibody DataSheet
Antibody Target: GDF-15
Target Alternative Name: MIC1; PDF; PLAB; PTGFB; Growth/differentiation factor 15; GDF-15; Macrophage inhibitory cytokine 1; MIC-1; NSAID-activated gene 1 protein; NAG-1; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic protein; Prostate differentiation factor
Tag Line: Affinity purified rabbit polyclonal antibody to detect GDF-15 expression in human, mouse, monkey and porcine samples
Category: Antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Porcine, Monkey, Mouse, Human
Immunogen Sequence: KLH-conjugated synthetic peptide targeting a sequence within the center region of human GDF15.
Accession #: Q99988
Gene ID: 9518
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification: Affinity purified
Application: Western Blotting
Positive Control:
Application And Usages: WB 1:500 - 1:1000
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: WB data verified using HepG2 and NIH3T3 whole cell lysates
Immunocytochemistry Verified: False
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
Additional Information
Size: |
100 uL |
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |