Anti- GLRA2 Antibody | FNab03487

Anti- GLRA2 Antibody | FNab03487 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:2155780, PubMed:15302677, PubMed:16144831, PubMed:23895467, PubMed:25445488) . Channel opening is also triggered by taurine and beta-alanine (PubMed:15302677) . Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488) . Plays a role in cellular responses to ethanol (PubMed:23895467) .

Immunogen: glycine receptor, alpha 2

synonyms: GLR, GLRA2, glycine receptor, alpha 2

Molecular weight (observed) : 48 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:500-1:1000; IHC: 1:20-1:200

Research Area: Neuroscience, Signal Transduction, Developmental biology