Description
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
A1884 | Anti-GPC3 Antibody DataSheet
Antibody Target: GPC3
Target Alternative Name: GPC3, SGBS, GTR2-2, DGSX, OCI-5, glypican-3, MXR7, SDYS, SGBS1, SGB
Tag Line: Affinity purified Rabbit polyclonal to GPC3
Category: Primary antibody
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Rat, Mouse, Human
Immunogen Sequence: Recombinant fusion protein containing a sequence corresponding to amino acids 290-550 of human GPC3 (NP_004475.1).
Accession #: P51654
Gene ID: 2719
Appearance: Liquid
Form: Liquid
Concentration:
Formulation: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Application: Immunofluorescence (IF), Western Blotting
Positive Control:
Application And Usages: WB 1:500 - 1:2000, IF 1:50 - 1:200
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: False
Immunofluorescence Verified: True
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
Additional Information
Size: |
100 uL |
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |