Anti-GPC3 Antibody | A1884

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

A1884 | Anti-GPC3 Antibody DataSheet

Antibody Target: GPC3

Target Alternative Name: GPC3, SGBS, GTR2-2, DGSX, OCI-5, glypican-3, MXR7, SDYS, SGBS1, SGB

Tag Line: Affinity purified Rabbit polyclonal to GPC3

Category: Primary antibody

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Rat, Mouse, Human

Immunogen Sequence: Recombinant fusion protein containing a sequence corresponding to amino acids 290-550 of human GPC3 (NP_004475.1).

Accession #: P51654

Gene ID: 2719

Appearance: Liquid

Form: Liquid

Concentration:

Formulation: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification: Affinity purification

Application: Immunofluorescence (IF), Western Blotting

Positive Control:

Application And Usages: WB 1:500 - 1:2000, IF 1:50 - 1:200

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: False

Immunofluorescence Verified: True

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False