Anti-GPC3 recMAb™ Antibody | A2190

Cell-surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

A2190 | Anti-GPC3 recMAb™ Antibody DataSheet

Antibody Target: GPC3

Target Alternative Name: Glypican proteoglycan 3, Heparan sulphate proteoglycan, Intestinal protein OCI-5, Secreted glypican-3, SGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2

Tag Line: Recombinant mouse monoclonal antibody to detect the expression of GPC3 in human and rat samples

Category: Primary antibody

Host: Mouse

Isotype: IgG1, kappa

Species Reactivities: Rat,Human

Immunogen Sequence: Recombinant full-length human GPC3 protein

Accession #: P51654

Gene ID: 2719

Appearance: Colorless liquid

Form: Liquid

Concentration: 1 mg/ml

Formulation: In 10 mM PBS

Purification: Protein A/G purified

Application: Immunohistochemistry (IHC),Immunofluorescence (IF),FACS

Positive Control:

Application And Usages: FC (1-2 µg/million cells), IF (1-2 µg/ml), IHC (1-2 µg/ml)

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: TRUE

Immunoprecipitation Verified: FALSE

FACS Verified: TRUE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE