710
Anti- GSDMD Antibody | FNab03670
- SKU:
- 710-FNab03670-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- GSDMD Antibody | FNab03670 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Immunogen: gasdermin D
synonyms: DF5L, DFNA5L, FKSG10, FLJ12150, gasdermin D, GSDMD, GSDMDC1
Molecular weight (observed) : 50-53 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, FC
Recomended Dillution : WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Research Area: Developmental biology