Anti-H2BK20me1 Antibody | A2058

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The protein has antibacterial and antifungal antimicrobial activity. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack poly A tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

A2058 | Anti-H2BK20me1 Antibody DataSheet

Antibody Target: H2BK20me1

Target Alternative Name: Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI, H2BFL; H2BFH; H2BFG; H2BFA; H2BFK

Tag Line: Rabbit polyclonal antibody to detect monomethylation of Histone H2B at Lysine 20 in human samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Human

Immunogen Sequence: Methylated peptide sequence targeting residues around Lysine 20 of human Histone H2B

Accession #: P62807

Gene ID: 8347

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In 0.01 M PBS, 50% glycerol, 0.03% proclin 300, pH 7.4

Purification: Antigen Affinity purified

Application: ChiP,Western Blotting

Positive Control:

Application And Usages: WB,1:100-1:1000

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: False

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: True

Dot Blot Verified: False

Flow Cytometry Verified: False