Anti-H3K18ac Polyclonal Antibody | A2359

Anti-H3K18ac Polyclonal Antibody | A2359

Description: Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called “histone code.” Acetylation of histone H3 is associated with active gene transcription, and acetylation of lysine 18 on histone H3 is associated with cancer prognosis.

Antibody Target: Human histone H3, acetylated at lysine 18

Target Alternative Name: H3 clustered histone 1; histone cluster 1 H3 Family Member A; Histone Cluster 1, H3a; Histone 1,; Histone H3.1; Histone H3/A; HIST1H3A

Tag Line: Polyclonal antibody that recognizes histone H3 acetylated at lysine 18, a putative tumor biomarker

Category: GM-CSF

Lot #:

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Clone#:

Species Reactivities: Mouse, Rat, Human

Immunogen Sequence: KLH-conjugated synthetic peptide surrounding N-terminal region of human histone H3 acetylated at lysine 18

Accession #: P68431

Gene Id: 8350

Form: Liquid

Appearance: Rabbit polyclonal

Concentration:

Formulation: Liquid in 0.42% potassium phosphate, 0.87% sodium chloride, pH 7.3, with 30% glycerol and 0.01% sodium azide

Purification: Immunogen affinity chromatography

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting

Positive Control: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting

Application And Usages:

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: TRUE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: TRUE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: TRUE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE