Anti-Human CD11b Monoclonal Antibody (AF488 Conjugated) | DL21785F

Anti-Human CD11b Monoclonal Antibody (AF488 Conjugated) | DL21785F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: Integrin alpha-M, Itgam, CD11 antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b

Reactivity: Human

Application: FCM

Background: CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.

Concentration: N/A

Conjugation: AF488

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: ICRF44

Isotype: Mouse IgG1, κ