Anti-Human CD184/CXCR4 Monoclonal Antibody (PE Conjugated) | DL21842F

Anti-Human CD184/CXCR4 Monoclonal Antibody (PE Conjugated) | DL21842F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: FB22, Fusin, HM89, LCR1, LAP-3

Reactivity: Human

Application: FCM

Background: CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.

Concentration: N/A

Conjugation: PE

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: 12G5

Isotype: Mouse IgG2a, κ