Anti-Human CD206 Monoclonal Antibody (FITC Conjugated) | DL21858F

Anti-Human CD206 Monoclonal Antibody (FITC Conjugated) | DL21858F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: CLEC13D, CLEC13DL, MRC1L1, MMR, hMR

Reactivity: Human

Application: FCM

Background: Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR) . It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity.

Concentration: N/A

Conjugation: FITC

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: 15, 2

Isotype: Mouse IgG1, κ