Anti-Human CD273/PD-L2 Monoclonal Antibody (APC Conjugated) | DL21929F

Anti-Human CD273/PD-L2 Monoclonal Antibody (APC Conjugated) | DL21929F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: B7DC, CD273, PDCD1L2, PDL2

Reactivity: Human

Application: FCM

Background: CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2) . This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.

Concentration: N/A

Conjugation: APC

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: 24F.10C12

Isotype: Mouse IgG2a, κ