Anti-Human CD54 Monoclonal Antibody (AF488 Conjugated) | DL20638F

Anti-Human CD54 Monoclonal Antibody (AF488 Conjugated) | DL20638F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: Intercellular adhesion molecule 1, Icam1, MALA-2, MyD10, CD54, Icam-1

Reactivity: Human

Application: FCM

Background: CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen.

Concentration: N/A

Conjugation: AF488

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: 15, 2

Isotype: Mouse IgG1, κ