Anti-Human CD62L Monoclonal Antibody (Biotin Conjugated) | DL20701F

Anti-Human CD62L Monoclonal Antibody (Biotin Conjugated) | DL20701F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: L-selectin, Sell, CD62 antigen-like family member L, LAM-1, LECAM1, Lymph node homing receptor, Ly-22, CD62L, Lnhr, Ly22

Reactivity: Human

Application: FCM

Background: CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

Concentration: 0.5 mg/mL

Conjugation: Biotin

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: DREG56

Isotype: Mouse IgG1, κ