Anti-Human FGFR-3 neutralizing Antibody | 500-002

Anti-Human FGFR-3 neutralizing Antibody | 500-002 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: E. coli

Comment: N/A

Label: N/A

Clone / Antibody feature: Recombinant IG

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: FGFR3; ACH; CEK2; JTK4; CD333; HSFGFR3EX

Isotype: Fab-Fragment

Application: N/A

Detection Range: N/A

Species Reactivity/Cross reactivity: human

Antigen: N/A

Description: Fibroblast Growth Factor Receptor 3 (FGF R3) is a type I transmembrane tyrosine kinase receptor that binds FGF ligands along with heparin or heparin sulfateproteoglycans as cofactors. A segment of the membrane proximal Ig-like domain can be encoded by two different exons resulting in (IIIb) or (IIIc) isoforms. The IIIb or IIIc isoforms recognize FGF1, 2, 4, 8b, 8e, 8f, 9, and 17b. FGF R3 plays a role in skeletal, brain, lung, intestine, kidney, and skin development.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for up to a year at -20°C. Upon reconstitution, the Fab is stable for up to 1 month at 4°C or up to 1 year at -20°C.

Reconstituation: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 2261