Anti-Human/Mouse/Rat CD47 Monoclonal Antibody (APC Conjugated) | DL20298F

Anti-Human/Mouse/Rat CD47 Monoclonal Antibody (APC Conjugated) | DL20298F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: Leukocyte surface antigen CD47, Cd47, Integrin-associated protein, IAP

Reactivity: Human, Mouse, Rat

Application: FCM

Background: CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

Concentration: N/A

Conjugation: APC

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: MIAP410

Isotype: Mouse IgG1, κ