710
Anti- Iduronate 2 sulfatase Antibody | FNab04130
- SKU:
- 710-FNab04130-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- Iduronate 2 sulfatase Antibody | FNab04130 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 2D2
Isotype: IgG1
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181) .
Immunogen: iduronate 2-sulfatase
synonyms: IDS, iduronate 2 sulfatase, Idursulfase
Molecular weight (observed) : 76 kDa, 55 kDa
Reactivity Species: Human
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Research Area: Cardiovascular, Metabolism