Anti- Iduronate 2 sulfatase Antibody | FNab04130

Anti- Iduronate 2 sulfatase Antibody | FNab04130 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 2D2

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181) .

Immunogen: iduronate 2-sulfatase

synonyms: IDS, iduronate 2 sulfatase, Idursulfase

Molecular weight (observed) : 76 kDa, 55 kDa

Reactivity Species: Human

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

Research Area: Cardiovascular, Metabolism