710
Anti- IL-10 Antibody | FNab10822
- SKU:
- 710-FNab10822-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- IL-10 Antibody | FNab10822 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
Immunogen: interleukin 10
synonyms: CSIF, IL 10, IL10, IL-10, IL10A, interleukin 10, TGIF
Molecular weight (observed) : 21 kDa
Reactivity Species: Hamster
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:500 - 1:2000
Research Area: Immunology, Cardiovascular, Signal Transduction