710
Anti- IL-4 Antibody | FNab09861
- SKU:
- 710-FNab09861-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- IL-4 Antibody | FNab09861 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Immunogen: interleukin 4
synonyms: BCGF-1
Molecular weight (observed) : Refer to figures
Reactivity Species: Human, Rat
Tested Application: ELISA, WB, IF
Recomended Dillution : WB: 1:500 - 1:1000
Research Area: Immunology, Cardiovascular, Signal Transduction