710
Anti- IL-6 Antibody | FNab04282
- SKU:
- 710-FNab04282-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- IL-6 Antibody | FNab04282 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
Immunogen: interleukin 6 (interferon, beta 2)
synonyms: B cell stimulatory factor 2, BSF 2, BSF2, CDF, CTL differentiation factor, HGF, HSF, Hybridoma growth factor, IFN beta 2, IFNB2, IL 6, IL6, IL-6, Interferon beta 2, Interleukin 6
Molecular weight (observed) : 24 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:50-1:200
Research Area: Neuroscience, Immunology, Cardiovascular, Signal Transduction