Anti- IL1R2 Antibody | FNab04243

Anti- IL1R2 Antibody | FNab04243 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 7G9

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

Immunogen: interleukin 1 receptor, type II

synonyms: CD121b, CDw121b, IL 1R 2, IL 1R beta, IL 1RT 2, IL 1RT2, IL1 Receptor 2, IL-1 Receptor 2, IL1 Receptor II, IL-1 Receptor II, IL1R2, IL1RB, IL-1RII, Interleukin 1 receptor beta, Interleukin 1 receptor type 2, Interleukin 1 receptor type II

Molecular weight (observed) : 45 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:500-1:2000; IF: 1:20-1:200

Research Area: Immunology, Signal Transduction